Coconut Oil Studies - Oral Health

14. 中鎖脂肪酸で、口腔内を健康にしましょう

1. ココナッツオイルとバージンココナッツオイル:口腔および全体的な健康への洞察

Coconut Oil and Virgin Coconut Oil: An Insight into its Oral and Overall Health Benefits



「Kavala Gandoosha」としても知られているオイルプリング療法は、口腔内での歯垢(プラーク)の形成を減らします。





Oral health is of prime importance to all individuals.

The traditional use of oil in India for maintenance of good oral hygiene has been mentioned in the Vedic literature since ancient times.

Oil pulling therapy also known as ‘Kavala Gandoosha’ is a traditional procedure involving rinsing or swishing of the oil in the mouth, which is said to have anti-inflammatory and antimicrobial effect thus reducing plaque formation in the oral cavity.

Coconut oil is an edible oil that is highly desired and easily available in India and has antimicrobial effect against a wide range of microorganisms found within the body. The growing popularity of Virgin Coconut Oil (VCO) has opened up new research in its clinical application apart from its role as functional food oil.

The present review aims to highlight the general benefits of coconut oil usage and the traditional concept of oil pulling with coconut oil as a supplemental oral hygiene aid and acknowledge the use of traditional medicine as part of primary healthcare

2. 歯科大学生を対象にして行ったココナッツオイルプリングとプラセボの抗歯垢効果の比較評価:無作為化比較試験

Comparative Evaluation of Antiplaque Efficacy of Coconut Oil Pulling and a Placebo, Among Dental College Students: A Randomized Controlled Trial.

3. オイルプリング:素晴らしいアーユルヴェーダ療法

Oil Pulling: A Wonderful Ayurvedic Therapy

4. 初期の浸食に関する後天性のエナメルペリクルに塗布した植物油効果について

Effect of vegetable oils applied over acquired enamel pellicle on initial erosion.

enamel pellicle(エナメルペリクル):エナメル質周囲の唾液糖タンパク質による薄膜

5. ストレプトコッカス・ミュータンスに関するピュアココナッツオイルプリングが影響:無作為化比較試験

The effect of oil pulling with pure coconut oil on Streptococcus mutans: A randomized controlled trial

Streptococcus mutans:ストレプトコッカス・ミュータンスは、グラム陽性で通性嫌気性のレンサ球菌の一種である。ヒトの口腔内にも存在し、う蝕(虫歯)の原因菌の一つで、1924年にJ Kilian Clarkeによって発見された。

6. 口腔(内)灼熱症候群での口腔乾燥症および口内発疹症の管理におけるオイルプリング療法のメリット

Merits of Oil Pulling Therapy in the Management of Xerostomia and Stomatopyrosis in Burning Mouth Syndrome







顎関節症/三叉神経痛/舌咽神経痛/スルーダー神経痛(翼口蓋神経痛) /フライ症候群/ファーストバイト症候群/非定型顔面痛



7. ストレプトコッカス・ミュータンスに関するココナッツオイルとクロルヘキシジンの抗菌効能の比較:in vivo試験

Comparison of antibacterial efficacy of coconut oil and chlorhexidine on Streptococcus mutans: An in vivostudy



Streptococcus mutansは、虫歯を引き起こす最も一般的な生物である。バクテリアの治療に役立つ様々な化学療法剤が利用可能であり、それぞれが独自のメリットとデメリットを持っています。



8-12歳の女性小児50名が研究に参加した。 25人の子供を各群、すなわち研究群(ココナッツオイル)および対照群(クロルヘキシジン)にランダムに分配した。


チアサイド法、すなわちDentocult SM Strip Mutans試験を用いて、唾液およびプラーク中のS. mutansを決定した。


S.ミュータンス。 1日目、15日目、および30日目のプラークおよび唾液中のカウントを記録し、結果をWilcoxonマッチドペアサインランク検定を用いて比較した。






ココナッツオイルは、S. mutansの減少においてクロルヘキシジンと同等に有効である。



Streptococcus mutans is the most common organism causing dental caries.

Various chemotherapeutic agents are available that help in treating the bacteria, with each having their own merits and demerits.

Recent research has shown that coconut oil has anti-inflammatory and antimicrobial action.

Therefore, the present was conducted to determine the antibacterial efficacy of coconut oil and to compare it with chlorhexidine.


A total of fifty female children aged 8-12 years were included in the study.

Twenty five children were randomly distributed to each group, i.e., the study group (coconut oil) and the control group (chlorhexidine).

The participants were asked to routinely perform oil swishing with coconut oil and chlorhexidine and rinse every day in the morning after brushing for 2-3 minutes. S. mutans in saliva and plaque were determined using a chairside method, i.e., the Dentocult SM Strip Mutans test. Patients were instructed to continue oil swishing for 30 days.

S. mutans. counts in plaque and saliva on day 1, day 15, and day 30 were recorded and the results were compared using Wilcoxon matched pairs signed ranks test.


The results showed that there is a statistically significant decrease in S. mutans. count from coconut oil as well as chlorhexidine group from baseline to 30 days.

The study also showed that in comparison of coconut oil and chlorhexidine there is no statistically significant change regarding the antibacterial efficacy.


Coconut oil is as effective as chlorhexidine in the reduction of S. mutans.

8. 口腔内衛生を維持するオイルプリング

Oil pulling for maintaining oral hygiene - A review.

9. oro歯科衛生推進でのオイルプリング効果:ランダム化臨床試験の体系的レビュー

Effect of oil pulling in promoting oro dental hygiene: A systematic review of randomized clinical trials.

10. 唾液中のStreptococcus mutans数について、クロルヘキシジン口腔内洗浄剤とココナッツオイルのオイルプリングとの効果比較

The Effect of Coconut Oil pulling on Streptococcus mutans Count in Saliva in Comparison with Chlorhexidine Mouthwash.

11. 幼児期虫歯のある幼児のカンジダアルビカンスに関するクロルヘキシジン、ココナッツオイル、プロバイオティクスおよびケトコナゾールの抗菌活性比較:インビトロ試験

Comparison of Antimicrobial Activity of Chlorhexidine, Coconut Oil, Probiotics, and Ketoconazole on Candida albicans Isolated in Children with Early Childhood Caries: An In Vitro Study

ケトコナゾール(Ketoconazole):真菌症の治療に使用されるイミダゾール系合成抗真菌薬の一つ。 白癬、カンジダ症、癜風等の治療に用いられる。






This study scientifically proves the antifungal activity of chlorhexidine, coconut oil, and probiotics.

The antifungal activity of coconut oil is found to be higher than that of probiotics

against C. albicans.

Further studies must be carried out to determine the antimicrobial efficacy, the MIC, and MFC of these agents and more clinicals have to be conducted to validate the same.

12. オイルプリング - 変装で支持

Oil Pulling - A Blessing in Disguise











Oil pulling is an ancient Ayurvedic remedy for oral health and detoxification.

It involves the use of pure oils as agents to cleanse out harmful bacteria, as well as reduce fungal overgrowth.

Oil pulling may also increase saponification in the mouth, creating a soapy environment that cleanses the mouth as vegetable fat is an emulsifier by nature.

Most interesting is perhaps the ability of oil to help in cellular restructuring, and are related to the proper functioning of the lymph nodes and other internal organs.

Apart from the various available scientific advancements in the medical field, there are age old traditional practices in Ayurvedic medicine which have to be encouraged. Oil pulling, which only requires one to swish oil in the mouth is known to cure many oral and systemic ailments.

Though oil pulling is effective, none of the studies considered it as a replacement for the tooth brushing, but can definitely be a supplemental oral hygiene aid.

This paper aims at throwing light on the various health benefits of this bygone practice.

13. 口腔内衛生のオイルプリング ー レヴュー

Oil pulling for maintaining oral hygiene - A review.

14. 妊婦の口臭に関する、米ぬか油、ごま油、そしてクロルヘキシジン口内のすすぎのオイルプリング効果:比較介入試験

The effect of oil pulling with rice bran oil, sesame oil, and chlorhexidine mouth rinsing on halitosis among pregnant women: A comparative interventional study


15. 日和見菌カンジダアルビカンスによる胃腸のコロニー形成を減少させる宿主食の操作について

Manipulation of Host Diet To Reduce Gastrointestinal Colonization by the Opportunistic Pathogen Candida albicans.

タフツ大学/Tufts Universityの研究者を中心とした研究により、ココナッツオイルは真菌病原体のカンジダ・アルビカンス/ Candida albicans (C. albicans) の過剰な増殖を効果的にコントロールすることがマウスの実験で明らかになった

ヒトの胃腸でカンジダ菌が過剰に増殖すると血流による感染につながり、侵襲性カンジダ症invasive candidiasisなどを引き起こすmSphere誌で発表された今回の研究は、カンジダ菌による感染リスクを低下させるために抗真菌剤の代わりとして使える食品によるアプローチを示唆するカンジダ菌は一般的な真菌病原体であり、胃腸の正常な微生物叢floraの一部である。普段は免疫系によって抑えられているが、免疫系が弱まると胃腸管を越えて広まり疾患を引き起こす日和見病原体であるカンジダ菌による全身感染は侵襲性カンジダ症を引き起こし、カンジダ感染は未熟児や高齢の患者など免疫の弱い患者で最も多い。


微生物学者のCarol Kumamoto、栄養科学者のAlice H. Lichtensteinを中心とする研究チームは、油脂がカンジダ菌の量に与える影響をマウスの腸で調査した研究に使われた油はココナッツオイル、牛脂、大豆油の三種類で、対照群のマウスには通常の食餌が与えられたココナッツオイルが選ばれた理由は、研究室の実験で真菌を抑える性質があったという以前の研究に基いている実験の結果、ココナッツオイルが豊富なエサは牛脂や大豆油のそれと比較して腸のカンジダ菌を減少させたココナッツオイル単独、またはココナッツオイルと牛脂の組み合わせは、牛脂が豊富なエサと比較して腸のカンジダ菌を90%以上も減少させました。


この発見は既存の患者の食事へのココナッツオイルの添加がカンジダ菌の腸での増殖をコントロールする可能性を示唆し、恐らくカンジダ菌による真菌感染リスクも低下させるだろう」タフツ大学医学部の分子生物学と微生物学の教授であるKumamoto, Ph.D.は言う

16. イヌおよびネコの歯周病菌に対する中鎖トリグリセリドの革新的エマルジョンの抗菌効力について

Antimicrobial efficacy of an innovative emulsion of medium chain triglycerides against canine and feline periodontopathogens.

periodontopathic bacteria:歯周病原菌


17. 歯肉炎に関係する歯垢(プラーク)に於けるココナッツオイル効果 - 予備的報告

Effect of coconut oil in plaque related gingivitis - A preliminary report.

18. OratestおよびDentocult SM Strip Mutansキットを用いたう蝕活動性とStreptococcus mutansの測定数値について、フッ化系マウスリンス、ハーブ系マウスリンス、そしてオイルプリングの各効果を比較した評価について

Comparative Evaluation of the Effects of Fluoride Mouthrinse, Herbal Mouthrinse and Oil Pulling on the Caries Activity and Streptococcus mutans Count using Oratest and Dentocult SM Strip Mutans Kit

19. スケイリングとルートプラニングの付属物としてのオイルプリングについて:臨床での微生物研究

Oil pulling as an adjunct to scaling and root planing: A Clinico-Microbial study

scaling and root planing:スケーリング終了後に、スケーラーを用い歯根表面の汚染・軟化されたセメント質や象牙質を除去し歯根面を硬く滑沢に仕上げることを目的とする歯周基本治療の一つ。 歯根面を硬く滑沢に仕上げることで、歯周炎の原因を取り除き、歯肉の再付着を促すことになる。

20. オイルプリングは、多くの細菌性感染症、ウイルス性感染症および真菌性感染症、多くの身体疾患の最良の治療法で、強力な免疫力を提供します。

Oil Pulling - The Best Cure for Many Bacterial, Viral and Fungal Infections, Many body Disorders and Provides strong immune System

21. 口臭に関するオイルプリングとクロルヘキシジンの比較効能:ランダム化比較試験。

Comparative efficacy of oil pulling and chlorhexidine on oral malodor: a randomized controlled trial.

22. 共通の病原性口腔内微生物に関する、オイルガムマッサージ療法効果 - ランダム化比較試験

Effect of oil gum massage therapy on common pathogenic oral microorganisms - A randomized controlled trial.

23. 口腔および全身性疾患におけるオイルプリングの役割 - レビュー記事

Oil Pulling and its Role in Oral and Systemic Diseases- A Review Article







Preventive medicine is gaining a lot of popularity today.

Apart from the various available scientific advancements in the medical field, there are age old traditional practices in Ayurvedic medicine which have to be encouraged. Oil pulling, which only requires one to swish oil in the mouth is known to cure many

oral and systemic ailments.

This article aims at highlighting this practice in preventing not only diseases of the mouth but also systemic diseases associated with oral pathogens.

24. オイルプリングと口腔の健康について

Oil Pulling and Oral Health: A Review

25. オイルプリング療法とココナッツオイルの役割

Oil Pulling Therapy and The Role of Coconut Oil







Oil pulling is a traditional remedy for many oral and systemic diseases.

Eventhough different edible oils are used, the scientific evidence for oil pulling is scarce.

Recent literature shows that coconut oil is effective for many systemic diseases and also against bacterial, viral and fungal infections because of the presence of Monolaurin, a medium chain fatty acid.

This article reviews the literature regarding oil pulling therapy and the use of coconut

oil in oil pulling therapy against oral diseases.

26. オイルプリング療法の有効性

Efficacy of Oil Pulling Therapy









We report a case report of 34 year old male who came with complaint of halitosis and loose tooth.

Examination revealed poor oral hygiene with sub gingival calculus.

Diagnosis of chronic generalized gingivitis with localized periodontitis was made.

A strict oral hygiene protocol was developed for maintaining oral hygiene status and oil pulling therapy was started as an integral part of the therapy.

We found a significant improvement in mobility of tooth due to bone regeneration and improved halitosis scores.

From this case report, it is evident that oil pulling therapy as an adjunct to oral hygiene protocolis efficient in treating periodontal diseases in future.

27. 歯科診療におけるオイルプリング療法の展望

Perspectives of oil pulling therapy in dental practice;year=2013;volume=4;issue=4;spage=131;epage=134;aulast=Lakshmi

オイルプリングに関する歯科医の視点 2018年1月26日










利点を発揮する為に、20分間のオイルスウィングが推奨されていますが、ほとんどの人にとってこれは非常に困難です。オイルはほぼ二倍になり、唾液はスウィング中に生成されるため、口を満たす。それが吐き出されると、一貫性はほとんどの人が習慣を続けるのはあまりにも不愉快です。 ADAが推奨するように、アルコールフリーのうがい薬を使用したスウィシュは、特に様々な味と強さで、ほとんどの人にとってははるかに容易です。



家庭でのケアをしても、歯科医の診察に代わるものはありません。 1年に2回、口腔保健ニーズに対応するために歯科医を見てください。

X線は潜在的な問題の徴候を示し、口腔ガンスクリーニングを実施することができ、詰め物、壊れた歯またはゆるい歯、顎の痛みなどの問題に対処できます。 '






ADAは、良好な歯科保健を維持するために、1日に1回、フッ化物練り歯磨きと歯間清掃を1日2回、タバコを使用しないことを推奨し続けています。」出典:ADA Oil Pulling


A Dentist’s Perspective on Oil Pulling

January 26, 2018

Oftentimes old trends resurface as new ones, get hype, and then disappear once again. Just think of the diet trends you’ve heard of in your lifetime – all wavering between the right and wrong foods, often naming the same foods in both lists. Everything in moderation, seems to be the direction that over arcs all trends, but is that true in regards to oil pulling? Here’s what your dentist has to say about it, including how oil pulling got started and alternate solutions.

coconut oil pullingWhat is oil pulling?

Oil pulling is an ancient Ayurvedic process that has gained popularity mostly by social media and celebrities who shout their testimonials. Proponents of the practice state it helps with everything from cleaning and detoxing the mouth (pulling toxins, thus the name oil pulling), whitening teeth, curing bad breath, and reducing inflammation that leads to conditions such as eczema, arthritis, and gum disease.

The practice simply involves swishing one’s mouth with high quality oil for 20 minutes a day. Organic coconut, sunflower, or sesame oils are the most often recommended.

Does oil pulling work?

Just like any natural remedy, true scientific studies and results are hard to come by. Likewise, there are those who claim huge benefits while others see none, and those who experience negative effects. Natural remedies are popular with those who want a more earth-based approach to health and wellness, so let’s look at how and why some people claim it works.

Why it works for some…and doesn’t for others

Proponents of oil pulling claim it whitens teeth and reduces plaque. But, these same benefits could also be accomplished with chewing sugar-free gum, using mouthwash, or even just rinsing with water for 20 minutes each day. All options can work to increase saliva or dilute the plaque concentration in a way that doesn’t allow it to stick to teeth.

To realize the benefits, twenty minutes of oil swishing is what is recommended, but for most people this is very difficult to do. The oil nearly doubles, filling your mouth as saliva is produced during the swishing. When it is spit out, the consistency is just too unpleasant for most people to continue the habit. Swishing with an alcohol-free mouthwash, as recommended by the ADA, is much easier for most people, especially with a variety of flavors and strengths.

Is oil pulling the solution for a healthy smile?

While oil pulling may remove some plaque, it truly needs to be removed with pressure, such as that from a toothbrush, floss, and dental tools. More ancient than oil pulling is that of chewing on a twig! These days, twice a day brushing, once a day flossing and mouthwash use, and even chewing of sugar-free gum after meals is recommended between dental visits for optimum health.

Even with good home care, nothing can replace a dentist visit. Twice a year, a dentist should be seen to address any oral health care needs. X-rays give indications of potential problems, oral cancer screenings can be conducted, and issues with fillings, broken or loose teeth, jaw pain, and more can be addressed. ‘

If you want the benefits of a whiter smile, have concerns about bad breath or gingivitis, talk to your dentist about natural solutions that will better match your unique situation.

What is the American Dental Association’s stand on oil pulling?

To be clear, here are their exact words:

“Currently, there are no reliable scientific studies to show that oil pulling reduces cavities, whitens teeth or improves oral health and well-being. Based on the lack of scientific evidence, the American Dental Association does not recommend oil pulling as a dental hygiene practice. The ADA continues to recommend that to maintain good dental health you brush twice a day for two minutes with fluoride toothpaste and floss between your teeth once a day and don’t use tobacco.” Source: ADA Oil Pulling

We think that speaks for itself, but if you have more questions or concerns, speak to your dentist. He or she knows your mouth and your situation and can discuss options with you based on that information. In need of a new dentist? Call us at 877-383-9923 to schedule your next appointment.

28. プラークが原因で発症する歯肉炎に関するゴマ油のオイルプリング効果:微生物学的研究

Effect of Oil Pulling with Sesame Oil on Plaque-induced Gingivitis: A Microbiological Study

29. ココナッツオイルは歯の腐敗を防ぎます。

Coconut Oil May Prevent Tooth Decay



Damien Brady博士とチームは、ココナッツオイルが一般的に人間の口に生息し、虫歯を引き起こすいくつかの連鎖球菌(Streptococcus)菌株に対抗して抗菌性を有するかどうかを決定しました。彼らはその天然および半消化状態のヤシ油を試験した。油を消化した状態で試験できるように酵素を添加しました。

天然の消化されていないココナッツオイルは影響を与えていないようだが、消化されたオイルが大部分のストレプトコッカス細菌の増殖を停止させることがわかった。特に興味深いのは、Streptococcus mutansであり、歯腐食酸を産生する細菌の一種である。










ストレプトコッカス・ミュータンス(Streptococcus mutans)(ストレプトコッカス・ミュータンス(S. mutans))は、嫌気性グラム陽性球菌の細菌である。コーカス・シェイプ(Coccus shaped)は、細菌が球形または回転楕円形であることを意味する。ストレプトコッカス・ミュータンス(S. mutans)はヒトの口腔に一般的に生息し、世界的に歯の腐敗の主要な原因である。

S. mutansは、専門家によれば、すべての口腔連鎖球菌の最も齲蝕原性が強い。齲蝕原性とは、虫歯の発症を引き起こすかまたは促進することを意味する。細菌は歯の表面に付着し、ある種の炭水化物に存在します。それは糖分や他のエネルギー源を代謝するので、歯に損傷を与える酸を生成します。


Coconut oil, a natural antibiotic when digested, destroys the bacteria that cause tooth decay, researchers at the Athlone Institute of Technology, Ireland, reported at the Society for General Microbiology's autumn conference at the University of Warwick, England, today. They added that the antibiotic component in digested coconut oil could be added to dental care products.

Dr Damien Brady and team set out to determine whether coconut oil might have antibacterial qualities at combating some strains of Streptococcus bacteria which commonly inhabit the human mouth and cause tooth decay. They tested the coconut oil in its natural and semi-digested state. They added enzymes so that the oil could be tested in a digested state.

Although natural, undigested coconut oil appeared to have no impact, the scientists found that the digested oil stopped most Streptococcus bacteria from multiplying. Of particular interest was Streptococcus mutans, a type of bacterium which produces teeth-decaying acids.

Dr. Brady explained that previous studies had demonstrated that certain foodstuffs, when semi-digested, had the capacity to destroy micro-organisms. The binding of S. mutans to tooth enamel was significantly reduced when teeth were exposed to enzyme-modified milk, one study had shown. That study encouraged this team to test out other foods.

The researchers plan to see how coconut oil interacts with Streptococcus bacteria at molecular level. They also want to find out whether digested coconut oil might combat other pathogens, including some types of bacteria and yeasts.

The team inform that preliminary studies have found that semi-digested coconut oil destroys Candida albicans, a yeast that causes thrush.

The scientists believe that enzyme-modified coconut oil, meaning in its semi-digested state, may have commercially viable antimicrobial qualities for the oral healthcare industry.

Dr Brady said:

"Dental caries is a commonly overlooked health problem affecting 60-90% of children and the majority of adults in industrialized countries. Incorporating enzyme-modified coconut oil into dental hygiene products would be an attractive alternative to chemical additives, particularly as it works at relatively low concentrations.

Also, with increasing antibiotic resistance, it is important that we turn our attention to new ways to combat microbial infection.

Our data suggests that products of human digestion show antimicrobial activity. This could have implications for how bacteria colonize the cells lining the digestive tract and for overall gut health.

Our research has shown that digested milk protein not only reduced the adherence of harmful bacteria to human intestinal cells but also prevented some of them from gaining entrance into the cell. We are currently researching coconut oil and other enzyme-modified foodstuffs to identify how they interfere with the way bacteria cause illness and disease."

Streptococcus mutans (S. mutans)

Streptococcus mutans (S. mutans) is an anaerobic, Gram-positive, coccus shaped bacterium. Coccus shaped means the bacterium has a spherical or spheroidal shape. S. mutans commonly inhabits the human oral cavity and is the leading cause of tooth decay globally.

S. mutans, according to experts, is the most cariogenic of all the oral streptococci. Cariogenic means producing or promoting the development of tooth decay. The bacterium sticks to the surface of the tooth and exists on certain types of carbohydrates. As it metabolizes sugars and other sources of energy, it produces an acid that damages teeth.

Virtually all humans carry S. mutans in their oral cavity.

30. オイルプリング:現代の古代習慣

Oil Pulling: An Ancient Practice for a Modern Time

31. 予防歯科医療での脂質の役割

Lipids in preventive dentistry.













OBJECTIVES:There is still a great demand for the improvement of oral prophylaxis methods. One repeatedly described approach is rinsing with edible oils.

The aim of the present review paper was to analyze the role of lipids in bioadhesion and preventive dentistry.

MATERIALS AND METHODS:Despite limited sound scientific data, extensive literature search was performed to illustrate possible effects of lipids in the oral cavity.

RESULTS:It is to be assumed that lipophilic components modulate the process of bioadhesion to the oral hard tissues as well as the composition and ultrastructure of the initial oral biofilm or the pellicle, respectively.

Thereby, lipids could add hydrophobic characteristics to the tooth surface hampering bacterial colonization and eventually decreasing caries susceptibility.

Also, a lipid-enriched pellicle might be more resistant in case of acid exposure and could therefore reduce the erosive mineral loss.

Furthermore, anti-inflammatory effects on the oral soft tissues were described. However, there is only limited evidence for these beneficial impacts.

Neither the lipid composition of saliva and pellicle nor the interactions of lipids with the initial oral biofilm and the pellicle layer have been investigated adequately until now.

CONCLUSION:Edible oils might qualify as mild supplements to conventional strategies for the prevention of caries, erosion, and periodontal diseases but further research is necessary.

CLINICAL RELEVANCE:Against the background of current scientific and empirical knowledge, edible oils might be used as oral hygiene supplements but a decisive benefit for the oral health status is questionable.

32. 短鎖脂肪酸および中鎖脂肪酸は、経口微生物に対して抗菌活性を示します。

Short- and medium-chain fatty acids exhibit antimicrobial activity for oral microorganisms.



方法:短鎖脂肪酸[ギ酸(C1)、酢酸(C2)、プロピオン酸(C3)、酪酸(C4)、イソ酪酸(C4)、イソ吉草酸(C5)、ヘキサン酸]、中鎖脂肪酸[オクタン酸(C8)、カプリン酸(C10)、ラウリン酸(12)]、および長鎖脂肪酸[ミリスチン酸(C14)、パルミチン酸(C16) Streptococcus mutans、Streptococcus gordonii、Streptococcus sanguis、Candida albicans、Aggregatibacter actinomycetemcomitans、Fusobacterium nucleatum、およびPorphyromonas gingivalisに対する抗菌活性を有する。






OBJECTIVES:This study assessed the antibacterial activity of short-, medium-, and long-chain fatty acids against various oral microorganisms.

METHODS:The short-chain fatty acids [formic acid (C1), acetic acid (C2), propionic acid (C3), butyric acid (C4), isobutyric acid (C4), isovaleric acid (C5), hexanoic acid (C6)], medium-chain fatty acids [octanoic acid (C8), capric acid (C10), lauric acid (12)], and long-chain fatty acids [myristic acid (C14), palmitic acid (C16)], were investigated for antimicrobial activity against Streptococcus mutans, Streptococcus gordonii, Streptococcus sanguis, Candida albicans, Aggregatibacter actinomycetemcomitans, Fusobacterium nucleatum, and Porphyromonas gingivalis.

RESULTS:The data demonstrated that the fatty acids exhibited patterns of inhibition against oral bacteria with some specificity that appeared related more to the bacterial species that the general structural characteristics of the microorganism. As a group the fatty acids were much less effective against C. albicans than the oral bacteria, with effectiveness limited to hexanoic, octanoic, and lauric acids. Formic acid, capric, and lauric acids were broadly inhibitory for the bacteria. Interestingly, fatty acids that are produced at metabolic end-products by a number of these bacteria, were specifically inactive against the producing species, whilst substantially inhibiting the growth of other oral microorganisms.

CONCLUSIONS:The results indicate that the antimicrobial activity of short-chain fatty acids (SCFAs), medium-chain fatty acids (MCFAs), long-chain fatty acids (LCFAs) could influence the microbial ecology in the oral cavity via at least 2 potential pathways. First, the agents delivered exogenously as therapeutic adjuncts could be packaged to enhance a microbial-regulatory environment in the subgingival sulcus. Second, it would be the intrinsic nature of these fatty acid inhibitors in contributing to the characteristics of the microbial biofilms, their evolution, and emergence of species within the biofilms. Further studies on these functions are required to better understand the nature of these potential microbial interactions in the biofilms.

33. 口臭とその発生原因である微生物に関するオイルプリング効果:無作為化試験パイロット試験

Effect of oil pulling on halitosis and microorganisms causing halitosis: a randomized controlled pilot trial.

34. 歯磨き、オイルプリング、組織再生:口腔衛生に対するホリスティックアプローチのレビュー。

Tooth brushing, oil pulling and tissue regeneration: A review of holistic approaches to oral health.


歯科医師はアーユルヴェーダの専門拠点ではありませんでしたが、それはShalakya Tantra(手術システム)に含まれています。





Amla(Emblic myrobalan)は、口腔衛生の一般的な再建者です。

ビルベリー果実(Vaccinium myrtillus)とサンザシ果実(Crateagus oxycanthus)はコラーゲンを安定化させ、ガム組織を強化します。

リコリス(Liquorice)根(Glycyrrhiza glabral)は、抗空洞作用を促進し、プラークを減少させ、抗菌効果を有する。伝統的な医学がプライマリヘルスケアの一部として認められるならば、入手可能な証拠に基づいて、安全で高品質な製品とプラクティスの使用が保証されるべきである。



Even though dentistry was not a specialized branch of Ayurveda, it is included in its Shalakya Tantra (system of surgery).

Problems such as deformities of the oral cavity, plaques and infections were managed in ancient India.

Traditional medicine can treat various infectious and chronic conditions.

Research has shown that all kinds of chewing sticks described in ancient Ayurveda texts have medicinal and anti-cariogenic properties.

Its oil pulling (Kaval, Gandush) practice is claimed to cure about 30 systemic diseases.

Amla (Emblic myrobalan), is a general rebuilder of oral health.

Bilberry fruit (Vaccinium myrtillus) and hawthorn berry (Crateagus oxycanthus) stabilize collagen, strengthening the gum tissue.

Liquorice root (Glycyrrhiza glabral) promotes anti-cavity action, reduces plaque, and has an antibacterial effect. Use of safe, quality products and practices should be ensured based on available evidence if traditional medicine is to be acknowledged as part of primary health care.

Scientific validations of the Ayurveda dental health practices could justify their incorporation into modern dental care.

Publicity of these techniques using appropriate media would benefit the general population by giving more confidence in the ancient practices, thus preventing tooth decay and loss.

35. オイルプリング療法のメカニズム - インビトロ研究

Mechanism of oil-pulling therapy - in vitro study.




材料および方法:(1)リグナンおよびゴマ油の抗菌活性を、寒天希釈法および寒天ウェル拡散法による最小阻害濃度アッセイによってそれぞれ試験した。 (2)油の遊離脂肪酸濃度の上昇と滴定で消費された水酸化ナトリウム(NaOH)の量が鹸化過程の良い指標である。これは、植物油の分析試験を用いて評価した。 (3)油の状態、微生物の存在、口腔の破片および異物を評価するために、澄んだ油を光学顕微鏡下で観察した。





BACKGROUND:Oil pulling has been used extensively as a traditional Indian folk remedy without scientific proof for many years for strengthening teeth, gums and jaws and to prevent decay, oral malodor, bleeding gums and dryness of throat and cracked lips.

AIM:The aim of this study was to evaluate the antibacterial activity of sesame oil and lignans isolated from sesame oil on oral microorganisms and to check whether saponification or emulsification occurs during oil-pulling therapy.

MATERIALS AND METHODS:The in vitro study was carried out in three different phases: (1) Antibacterial activity of the lignans and sesame oil were tested by minimum inhibitory concentration assay by agar dilution method and agar well diffusion method, respectively. (2) Increase in free fatty acid level of oil and the quantity of sodium hydroxide (NaOH) used up in the titration are good indicators of saponification process. This was assessed using analytical tests for vegetable oils. (3) Swished oil was observed under light microscope to assess the status of the oil, presence of microorganisms, oral debris and foreign bodies.

RESULTS:Sesamin and sesamolin isolated from sesame oil did not have any antibacterial effect against oral microorganisms like Streptococcus mutans, Streptococcus mitis and Streptococcus viridans. Emulsification of sesame oil occurs during oil-pulling therapy. Increased consumption of NaOH in titration is a definite indication of a possible saponification process.

CONCLUSION:The myth that the effect of oil-pulling therapy on oral health was just a placebo effect has been broken and there are clear indications of possible saponification and emulsification process, which enhances its mechanical cleaning action.

36. 歯科医学とアーユルヴェーダV - エビデンスに基づくアプローチ

Dentistry & Ayurveda V - An evidence based approach


アーユルヴェーダの薬物治療は長年にわたって賞賛されており、様々な病気に大昔から使われていました。 近年、口腔および歯の健康のための様々なアーユルヴェーダ薬の使用が新たに関心を集めている。 抗炎症、抗菌、抗酸化特性などの薬理学的応用に使用されている以前からの植物および天然産物。この論文は、口腔疾患および天然物の最近の研究 アユルヴェーダ、歯科、天然製品、補完的/統合的な医学


Ayurvedic medications have stood the test of time and since time immemorial been used for various ailments. Recently there is renewed interest in use of various ayurvedic drugs for oral and dental health. . Plants and natural products from time immemorial used for their pharmacological applications viz., antiulcerogenic, wound healing, anti-inflammatory, antimicrobial, antioxidant properties etc. This article attempts to review the recent studies undertaken to use of natural products for oral diseases and also looks into the multitude prospects and perspectives of ayurveda in dentistry.Keywords: Ayurveda, dentistry, natural products, complementary/integrative medicine

37. ヴァージンココナッツオイルの抗炎症、鎮痛、および解熱活性

Anti-inflammatory, analgesic, and antipyretic activities of virgin coconut oil.


本研究では、化学的または高熱処理をしていないココナッツ(Cocos nucifera Linn(Palmae))ミルクの天然純粋油であるバージンココナッツオイル(VCO)の薬理学的特性を調べた。


急性炎症モデルにおいて、VCOは、フェニルプロピオン酸エチル誘発耳浮腫のラットにおける中等度の抗炎症効果、およびカラゲニンおよびアラキドン酸誘発足浮腫を示した。 VCOは、滲出重量、肉芽腫形成、および血清アルカリ性ホスファターゼ活性を低下させることで、慢性炎症に対する阻害効果を示した。 VCOはまた、酢酸誘発発熱に対する適度な鎮痛効果ならびに酵母誘発温熱療法における解熱効果を示した。 得られた結果は、VCOの抗炎症性、鎮痛性および解熱性を示唆している。


This study investigated some pharmacological properties of virgincoconutoil(VCO), the natural pure oilfrom coconut[Cocos nucifera Linn (Palmae)] milk, which was prepared without using chemical or high-heat treatment. The anti-inflammatory, analgesic, and antipyretic effects of VCO were assessed. In acute inflammatory models, VCO showed moderate anti-inflammatoryeffects on ethyl phenylpropiolate-induced ear edema in rats, and carrageenin- and arachidonic acid-induced paw edema. VCO exhibited an inhibitory effect on chronic inflammation by reducing the transudative weight, granuloma formation, and serum alkaline phosphatase activity. VCO also showed a moderate analgesic effect on the acetic acid-induced writhing response as well as an antipyretic effect in yeast-induced hyperthermia. The results obtained suggest anti-inflammatory, analgesic, and antipyretic properties of VCO.

38. オイルプリング - 神秘的な治療への道のりを解明する

Oil pulling-Unraveling the path to mystic cure

39. 歯垢(プラーク)が原因の歯肉炎に対するオイルプリング効果:無作為化、制御、トリプルブラインド研究

Effect of oil pulling on plaque induced gingivitis: a randomized, controlled, triple-blind study.

40. 口腔栄養療法は、胸腔治療に効果的ですか? 症例報告。

Is oral nutritional therapy effective for the treatment of chylothorax? A case report.

Chylothorax乳糜胸:乳麋(腸管からの脂肪球を含むリンパ球)が胸管より濾出して,胸腔内に貯留した状態をいうが,その原因として外傷や胸管の圧迫,閉. 塞,還流異常,または先天性や特発性など様々なものが. 考えられる

41. Dentocult SM Strip mutans試験で、プラークおよび唾液中のストレプトコッカス・ミュータンス菌の数値測定したオイルプリング効果:無作為化、コントロール、トリプルブラインド試験

Effect of oil pulling on Streptococcus mutans count in plaque and saliva using Dentocult SM Strip mutans test: a randomized, controlled, triple-blind study.

Streptococcus mutansストレプトコッカス・ミュータンス:グラム陽性で通性嫌気性のレンサ球菌の一種である。ヒトの口腔内にも存在し、う蝕(虫歯)の原因菌の一つ。1924年にJ Kilian Clarkeによって発見された。

42. バクテリアを発生させる虫歯へのオイルプリング効果

Effect of oil-pulling on dental caries causing bacteria

43. オイルプリング療法

Oil pulling therapy;year=2008;volume=19;issue=2;spage=169;epage=169;aulast=Asokan







Pedaliaceae科のゴマ植物(Sesamum indicum)は、その栄養的性質および多くの望ましい健康効果のために、人類への自然の贈り物と考えられてきました。植物の種子は、一般的に「gingelly」または「til」種子として知られています。

ごま油は高濃度の多価不飽和脂肪酸を持ち、ビタミンEの良い供給源です。[1]それに含まれる抗酸化物質は、主にセサモール、セサミン、セサモリンです。 [1]セサミンは、コレステロールの吸収および肝臓でのその産生を阻害することが判明しています。

脂質生成を減少させ、抗高血圧作用を示す。 [2]

Oil pullingまたはオイルスウィージングは口腔内のオイルを吸入して経口および全身の健康上の利益を得る方法です。

ゴマ油を用いたオイルプリング療法は、歯、歯茎、顎を強化し、歯の腐敗、口臭、出血性歯茎、喉の乾燥、ひび割れた唇の予防のために、伝統的なインドの民間療法として広く使用されてきました。 [3]オイルプリングの概念は新しいものではなく、アーユルヴェーダのテキストCharaka Samhitaで議論されています。

ここでは、それはkavala grahaまたはkavala gandooshaと呼ばれています。 [4]


スワイキングは酵素を活性化し、血液から毒素を引き出すと主張されている。 [3]








There may have been great technological advances in health care, but it is important not to lose sight of the basic protocols of patient care. In the field of dentistry this means establishing and maintaining effective preventive habits in our patients. No matter how sophisticated dental techniques and procedures may have become, preventive dentistry remains the foundation of oral health care. Dental health care professionals need to put home oral hygiene at the core of their advice on preventive practices. The area of oral hygiene has undergone humongous development, and a mundane subject has turned into a field with a surprising amount of growth and research. There are umpteen number of indigenous natural medicinal products which deserve due recognition for their contribution to improving oral health.

The sesame plant (Sesamum indicum) of the Pedaliaceae family has been considered a gift of nature to mankind because of its nutritional qualities and its many desirable health effects. The seeds of the plant are commonly known as 'gingelly' or 'til' seeds. Sesame oil has a high concentration of polyunsaturated fatty acids and is a good source of vitamin E. [1]The antioxidants present in it are mainly sesamol, sesamin, and sesamolin. [1]Sesamin has been found to inhibit the absorption of cholesterol as well as its production in the liver. It reduces lipogenesis and exhibits an antihypertensive action. [2]

'Oil pulling' or oil swishing is a procedure that involves swishing oil in the mouth for oral and systemic health benefits. Oil pulling therapy with sesame oil has been extensively used as a traditional Indian folk remedy for many years for strengthening teeth, gums, and jaws and to prevent tooth decay, oral malodor, bleeding gums, dryness of throat, and cracked lips. [3]The concept of oil pulling is not new and it has been discussed in the Ayurvedic text Charaka Samhita, where it is referred to as kavala grahaor kavala gandoosha. [4]For oil pulling therapy, a tablespoon (teaspoon for young children) of sesame oil is taken in the mouth, sipped, sucked, and pulled between the teeth for 10-15 min. The viscous oil turns thin and milky white. It is claimed that the swishing activates enzymes and draws toxins out of the blood. [3]The oil should not be swallowed as it contains bacteria and toxins. Oil pulling therapy should be followed by tooth brushing and rinsing of the mouth. It is preferably done on an empty stomach in the morning.

The question to be answered here is: 'Why is oil pulling being popularized?' Sesame oil has the following advantages over the standard and commercially available mouthwashes: it causes no staining, has no lingering aftertaste, and causes no allergic reactions. It is five to six times more cost-effective than the commercially available mouthwashes and is, moreover, readily available in the household. Considering these benefits, oil pulling therapy with sesame oil should be promoted as a measure for the prevention of oral disease. Sufficient scientific research has not been carried out to evaluate the effect of oil pulling therapy on oral health and this needs to be addressed. The answer to the above question is: 'If we do not support our desi product, who else will?' In the very near future, sesame oil will open new doors in oral health care.

44. ナイジェリアのIbadanに於ける、カンジダ種に関するココナッツオイルのin vitro抗菌特性

In vitro antimicrobial properties of coconut oil on Candida species in Ibadan, Nigeria.

45. プラークおよび歯肉炎に関するオイルプリング効果

Effect of Oil Pulling on Plaque and Gingivitis

46. 脂肪酸およびモノグリセリドによるカンジダ・アルビカンスのインビトロ死滅

In vitro killing of Candida albicans by fatty acids and monoglycerides.

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